Postdoc in lung-to-brain mast cell regulation in asthma - DTU Bioengineering

We seek a postdoc with expertise in mast cells and/or allergic immune regulation to join our mission to improve the lives of individuals experiencing brain fog in airway allergy and asthma.
Are you the next pioneer in the immunology of airway allergy and asthma?
We are seeking a curious, talented and pro-active postdoc with a background in immunology, neuroimmunology and/or neurology to join our mission to significantly improve the everyday life of individuals experiencing brain fog in airway allergy and asthma. The Department of Biotechnology and Biomedicine at the Technical University of Denmark invites applications for an 18-months postdoc position starting 1 December 2024 or as soon as possible.

About the postdoc project
As a postdoc focusing on mast cell regulation in the lung and at the brain borders, you will get a unique opportunity to contribute to pioneering research within lung-to-brain immunology. Specifically, you will work on a project that aims to determine the role for brain border mast cells and histamine in the symptoms of brain fog in airway allergy and asthma. The position involves ample opportunities for personal development, and you will develop new methods and use state-of-the-art techniques. You are in turn encouraged to take part in teaching and supervision opportunities.

Your main tasks will be

• To develop, optimize, and test models for tissue-specific immune cell characterization.
• To design and execute single cell and high-dimensional flow cytometry experiments.
• To assess behavior in allergic asthma in vivo models.
• To maintain genetically modified in vivo models.
• To perform independent research and to publish findings of high international quality.
• To contribute to student supervision and collaborative projects.
• To present findings at scientific conferences and in scientific publications.

The project is funded by an LF experiment grant from the Lundbeck Foundation and will be supervised by Assistant Professor Anna Hammerich Thysen.

Your competences
To thrive in the position, you bring:

• A PhD degree (or equivalent) in Immunology, Neuroimmunology, or Neurology.
• A proficiency in single cell analysis, immunohistochemistry, and/or flow cytometry.
• A flair for computational analysis of larger data sets.
• A curious mind and an enthusiasm for science.
• An interest in developing new experimental procedures.
• A pro-active and problem-solving approach to science.
• An ability to drive independent research projects.
• A willingness to positively interact and collaborate with colleagues.
• A persistence to work on challenging tasks.
• A track-record of publication in peer-reviewed journals.

You are not expected to enter with a full range of technical skills but experience with the following tasks is a plus:

• Imaging and/or histology.
• In vivo models of airway or allergic diseases.
• Assessment of animal behavior.
• Primary immune cell isolation and culture.
• qPCR.
• ELISA.
• Genotyping.

About the research group
You will join a highly driven and cross-functional research team. Your daily work will be led by Assistant Professor Anna Hammerich Thysen, and you will work closely with another postdoc, MSc students, and lab technicians. The group is embedded in the research group Disease Systems Immunology group in Section for Medical Biotechnology, led by Head of Section, Professor Susanne Brix Pedersen that offers an interdisciplinary, dynamic, and collaborative research environment with a focus on providing a supportive milieu for advancing your scientific career. Read more at http://bioengineering.dtu.dk/dsim

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 18 months. Starting date is 1 December 2024. The position is a full-time fixed term position.

You can read more about career paths at DTU here.
Further information
Request for further information and informal enquiries can be directed to Assistant Professor Anna Hammerich Thysen ([email protected]).

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 25 September 2024 (23.59 Danish time). Applications will be reviewed on an ongoing basis.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• A cover letter describing your ambition, motivation, and how you fit into the project.
• Detailed curriculum vitae (CV),
• List of publications,
• Academic Diplomas (MSc/PhD – in English)

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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